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PotM - July 2026
Therapeutic inhibition of telomeric DNA damage response rescues hematopoietic dysfunction driven by telomere shortening and aging Opezzo, A. et al., Nature Aging 2026 Brief Summary from the authors: What if some consequences of aging are driven not by the damage itself, but by the alarm signals our cells generate in response to it? More than 20 years ago, we discovered that dysfunctional telomeres activate a DNA damage response (DDR), driving cellular senescence and inflammat

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4 days ago2 min read
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