Therapeutic inhibition of telomeric DNA damage response rescues hematopoietic dysfunction driven by telomere shortening and aging Opezzo, A. et al., Nature Aging 2026 Brief Summary from the authors: What if some consequences of aging are driven not by the damage itself, but by the alarm signals our cells generate in response to it? More than 20 years ago, we discovered that dysfunctional telomeres activate a DNA damage response (DDR), driving cellular senescence and inflammat

Deadline 31st of August! 5th ICSA DEI Travel Fellowship for ICSA2026 Deadline: 31st August 2026 Who can apply: Our DEI Travel Fellowship is open to paid ICSA Members who self-identify with at least one facet of our Diversity Wheel. Other eligibility criteria apply. The award: up to 1000 EUR towards travel and accommodation to attend the conference, free registration to ICSA2026 and a ticket to the Gala Dinner. How to apply: Full details on eligibility, the funding, the timeli

Transcription-independent induction of rapid-onset senescence is integral to healing Valdivieso, K., Rozmaric, T., et al., Nature Cell Biology 2026 "Rapid senescence" Brief Summary: The study by Karla Valdivieso and Tomaž Rozmarič from the group of Mikolaj Ogrodnik tells the story of unexpected helpers: fast arising senescent cells that drive wound healing. The authors show that cells can enter a senescent state within minutes to hours after injury, much faster than previousl

Urinary detection of therapy-induced senescence and fibrosis using an injectable albumin-based nanoprobe Hartono M et al., Nature Aging 2026 Brief Summary provided by the authors: A novel urine test has been developed to detect a biochemical signal associated with senescence-related processes in diseased lung tissue. Matrix metalloproteinase-7 (MMP-7) was identified as a key marker linked to senescence-associated activity in lung cancer biology, particularly in the context of

Dear ICSA Members, We are happy to announce that we are opening registration for the Wiggers-Bernard Conference Senescence in vivo,...

The organizers have officially announced the first details of the ICSA2023 conference in Minneapolis, MN (USA). The conference will be...

Today at the annual ICSA meeting in Groningen (NL), Paul Robbins announced that the next conference will be organised in the USA by the...

YAP/TAZ activity in stromal cells prevents ageing by controlling cGAS–STING Hanna Lucie Sladitschek-Martens, Alberto Guarnieri, Giulia...

TRPC3 shapes the ER-mitochondria Ca 2+ transfer characterizing tumour-promoting senescence Valerio Farfariello, Dmitri V. Gordienko, Lina...

Dynamic regulation of myofibroblast phenotype in cellular senescence Irene López-Antona,Constanza Contreras-Jurado,Laura...

ICSA Steering Committee members recognized for their outstanding contribution. During the General Assembly at the end of the ICSA2021...

The dates and place for the next ICSA Conference have been announced

There is still time to register and submit an abstract. yICSA Senescence Symposium 2022 You are warmly invited to a one-day Senescence...

Senolytic vaccination improves normal and pathological age-related phenotypes and increases lifespan in progeroid mice Masayoshi Suda,...